Table 5.

Anti-Inflammatory Effect of 80% Methanolic Leaf Extracts of V. auriculifera on Carrageenan-Induced Paw Edema in Rats

Change in Paw Volume (mL) (Mean ±S.E.M) (Percent Inhibition %)
Group	Basal Volume	1 Hour	2 Hours	3 Hours	4 Hours
TW	0.61 ± 0.01	1.13 ± 0.02	1.21 ± 0.01	1.18 ± 0.02	1.16 ± 0.00
ME100	0.65 ± 0.01	1.04 ± 0.01 (7.9)a	0.86 ± 0.01 (28.9)a	0.83 ± 0.01 (29.6)a	0.76 ± 0.03 (34.4)a
ME200	0.64 ± 0.00	1.02 ± 0.01 (9.7)a	0.85 ± 0.01 (29.7)a	0.85 ± 0.02 (27.9)a	0.69 ± 0.01 (40.5)a
ME400	0.65 ± 0.01	0.94 ± 0.01 (16.8)abc	0.77 ± 0.00 (36.3)abc	0.72 ± 0.00 (38.9)abc	0.60 ± 0.01 (48.2)abc
IND	0.65 ± 0.01	0.78 ± 0.01 (30.9)abcd	0.76 ± 0.01 (37.1)abc	0.67 ± 0.00 (43.2)abc	0.56 ± 0.01 (51.7)abc

Notes: ^aAgainst TW, ^bagainst ME 100mg/kg, ^cagainst ME 200mg/kg, ^dagainst ME 400mg/kg; TW, 2% Tween 80 10mL/kg; ME, 80% methanol extract; IND, Indomethacin 10mg/kg; p < 0.05.