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. Author manuscript; available in PMC: 2023 Jan 31.
Published in final edited form as: Arch Biochem Biophys. 2022 Nov 25;733:109472. doi: 10.1016/j.abb.2022.109472

Fig. 5.

Fig. 5.

Map of network of h12-LOX derived peptides with altered exchange patterns emerging from the Y649C SNP (A). Panel (B) is rotated 90° with respect to A along the y-axis. Panel (C) represents the cartoon model of space-filling mode from (B) and has the site of mutation, iron center, and L407 represented as spheres and labeled for reference. The peptide coloring is reproduced from Fig. 4. Panel (D) displays the predicted packing environment surrounding Y649, which is represented as yellow spheres.