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Distribution of products created by reaction of either WT h12-LOX or Y649C with AA or DHA (10 μM). Percent values are presented. Standard deviation errors are shown in parentheses from 3 replicates.
| AA Products |
DHA Products |
|||||
|---|---|---|---|---|---|---|
| 12- HETE |
15- HETE |
14- HDHA |
17- HDHA |
20- HDHA |
11- HDHA |
|
| WT | 88 (2) | 12(2) | 76 (2) | 11 (0.5) | 0 | 13 (2) |
| Y649C | 81 (1) | 19(1) | 74 (2) | 8(2) | 8(1) | 10(1) |
