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. 2023 Jan 28;30(1):2168794. doi: 10.1080/10717544.2023.2168794

Table 3.

Fitting table of various indicators.

Response Model Source Sum of squares df Mean square F value p value  
Drug loading Linear model Model 290.35 2 145.18 15.06 .0004 Significant
(1)Linear mixture 290.35 2 145.18 15.06 .0004  
Residual 125.29 13 9.64      
Lack of fit 52.88 8 6.61 0.4564 .8450 Not significant
Pure error 72.41 5 14.48      
Cor total 415.64 15        
Solutions Linear model Model 5.20 2 2.60 35.17 <.0001 Significant
(1)Linear Mixture 5.20 2 2.60 35.17 <.0001  
Residual 0.9606 13 0.0739      
Lack of Fit 0.5411 8 0.0676 0.8061 .6263 Not significant
Pure Error 0.4195 5 0.0839      
Cor Total 6.16 15        
time Quadratic model Model 4.931 E + 05 5 98626.17 7.62 .0034 Significant
(1)Linear Mixture 93897.03 2 46948.52 3.63 .0654  
AB 3.714 E + 05 1 3.714E + 05 28.69 .0003  
AC 3293.05 1 3293.05 0.2544 .6249  
BC 1448.40 1 1448.40 0.1119 .7449  
Residual 1.294 E + 05 10 12943.19      
Lack of Fit 76315.64 5 15263.13 1.44 .3503 Not significant
Pure Error 53116.25 5 10623.25      
Cor Total 6.226 E + 05 15