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. 2023 Jan 31;18(1):e0268428. doi: 10.1371/journal.pone.0268428

Table 2. Distribution of different outcomes according to two arms in addition to related effect sizes.

Clinical Outcome PPT group (n = 19) Basic care group (n = 18) F (P value) ** MD [95% CI] SMD [95% CI] Partial eta2
Baseline* After* Baseline* After*
pO2 (mmHg) 29.4 ± 5.3 38.7 ± 5.3 30.6 ± 8.2 32.9 ± 7.5 7.5 (< .01) a 5.81 [1.51, 10.11] .9 [.21, 1.57] .177
13 (< .01) b 6.43 [2.8, 10.07] 1.18 [.48, 1.88] .276
12.04 (< .01) c 6.39 [2.64, 10.14] 1.15 [.45, 1.84] .267
pCO2 (mmHg) 40 ± 7.3 37 ± 7.2 39.3 ± 8 38.6 ± 8.1 .44 (.51) a -1.68 [-6.8, 3.44] -.22 [-.43, .86] .012
.97 (.33) b -2.1 [-6.36, 2.21] -.32 [-.97, .33] .027
.62 (.44) c -1.7 [-6.01, 2.65] -.26 [-.91, 39] .018
Spo2 (Free air) (%) 83.4 ± 4.9 90.21 ± 3.4 84.4 ± 3.9 86.2 ± 4 10.63 (< .01) a 3.99 [1.5, 6.47] 1.07 [.37, 1.76] .233
14.2 (< .01) b 4.43 [2.04, 6.83] 1.25 [.53, 1.95] .294
Distance of 3MWT (m) 46 ± 24.3 149.1 ± 63 50 ± 24.4 67.3 ± 33.1 24.03 (< .01) a 81.82 [47.93, 115.7] 1.61 [.86, 2.35] .407
67.9 (< .01) b 91.44 [68.88, 113.99] 2.72 [1.81, 3.62] .666
64.33 (< .01) c 91.62 [68.38, 114.86] 2.67 [1.76, 3.55] .661
Level of Dyspnea 5 ± 2 1.54 ± 1.2 5.19 ± 1.4 3.6 ± 1.5 22.89 (< .01) a -2.08 [-2.96, -1.19] -1.57 [-2.31, -.82] .395
38.44 (< .01) b -1.98 [-2.63, -1.33] -2.04 [-2.83, -1.23] .531
36.54 (< .01) c -1.99 [-2.66, -1.32] -2 [-2.79, -1.2] .525
RPE after Walking 16.2 ± 1.6 10.8 ± 3 17 ± 1.3 14.8 ± 2 22.6 (< .01) a -4.04 [-5.76, -2.32] -1.56 [-2.3, -.82] .393
18 (< .01) b -3.46 [-5.12, -1.8] -1.42 [-2.14, -.69] .346
15.67 (< .01) c -3.32 [-5.03, -1.62] -1.34 [-2.05, -.62] .322
PH from VBG 7.42 ± .08 7.5 ± .07 7.44 ± .06 7.43 ± .1 5.11 (.03) a .06 [.01, .12] .74 [.71, 1.41] .127
8.38 (< .01) b .08 [.02, .13] .96 [.27, 1.63] .198
7.31 (< .01) c .07 [.02, .13] .9 [.22, 1.57] .181

PPT: Pulmonary physiotherapy; pO2: Mixed venous O2 pressure; pCO2: Mixed venous CO2 pressure; Spo2: Oxygen saturation; 3MWT: Three-minute walk test; RPE: Rating of perceived exertion; VBG: Venous blood gas; MD: Mean difference; CI: Confidence interval; SMD: Standardized mean difference (based on Cohen’s d test), ANOVA: Analysis of variance, ANCOVA: Analysis of covariance.

* Expressed as mean ± standard deviation. The baseline and after values present the result of participants’ assessment before and after three days, respectively.

** Analyzed using ANOVA/ANCOVA tests. F statistics and P value were reported based on Group source analysis.

a Crude analysis.

b Adjusted to baseline measurement of the variable (as covariance).

c Adjusted t baseline measurement of the variable and baseline O2 saturation (free air) (as covariance).