Figure 2. Gene ontology (GO) analysis of hits obtained in a CRISPR-mediated loss-of-function screen in polarized CaCo2 cells.

(A) Schematic representation of significantly enriched genes obtained from a CRISPR screening approach, grouped and organized according to their associated GO terms. (B) GO association analysis of the seven factors that were chosen for CRISPR screen readout validation and further characterization. CC, cellular compartment; MF, molecular function; BP, biological process.