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. 2022 Dec 2;4(48):1083–1087. doi: 10.46234/ccdcw2022.218

Table 2. Association of HPV infection pattern with high-grade cervical intraepithelial neoplasia in cases.

Model Dependent
variable
Ordinal logistic regression
for CIN 1, 2, and 3
Binomial logistic regression
for CIN2/3 vs. CIN1
Binomial logistic regression
for CIN3 vs. CIN1/2
OR (95% CI) P OR (95% CI) P OR (95% CI) P
Abbreviation: CIN=cervical intraepithelial neoplasia; HPV=human papillomavirus; OR=odds ratio; CI=confidence interval.
Model 1 HPV negative Reference Reference Reference
Other HPV types
(no HPV-16/18)
2.14 (1.54−2.99) <0.001 2.15 (1.54−3.02) <0.001 2.12 (1.28−3.50) 0.003
HPV-16/18 5.51 (3.92−7.73) <0.001 5.74 (4.04−8.15) <0.001 5.07 (3.09−8.32) <0.001
Model 2 HPV negative Reference Reference Reference
Other HPV types
(no HPV-16/18)
2.17 (1.55−3.02) <0.001 2.17 (1.54−3.03) <0.001 2.13 (1.29−3.52) 0.003
HPV-16 related 6.96 (4.92−9.84) <0.001 7.48 (5.19−10.76) <0.001 6.12 (3.71−10.08) <0.001
HPV-18 related
(no HPV-16)
1.33 (0.76−2.31) 0.305 1.40 (0.80−2.46) 0.296 0.92 (0.37−2.29) 0.864