Table 2. Association of HPV infection pattern with high-grade cervical intraepithelial neoplasia in cases.
| Model |
Dependent
variable |
Ordinal logistic regression
for CIN 1, 2, and 3 |
Binomial logistic regression
for CIN2/3 vs. CIN1 |
Binomial logistic regression
for CIN3 vs. CIN1/2 |
|||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||||
| Abbreviation: CIN=cervical intraepithelial neoplasia; HPV=human papillomavirus; OR=odds ratio; CI=confidence interval. | |||||||||
| Model 1 | HPV negative | Reference | Reference | Reference | |||||
| Other HPV types (no HPV-16/18) |
2.14 (1.54−2.99) | <0.001 | 2.15 (1.54−3.02) | <0.001 | 2.12 (1.28−3.50) | 0.003 | |||
| HPV-16/18 | 5.51 (3.92−7.73) | <0.001 | 5.74 (4.04−8.15) | <0.001 | 5.07 (3.09−8.32) | <0.001 | |||
| Model 2 | HPV negative | Reference | Reference | Reference | |||||
| Other HPV types (no HPV-16/18) |
2.17 (1.55−3.02) | <0.001 | 2.17 (1.54−3.03) | <0.001 | 2.13 (1.29−3.52) | 0.003 | |||
| HPV-16 related | 6.96 (4.92−9.84) | <0.001 | 7.48 (5.19−10.76) | <0.001 | 6.12 (3.71−10.08) | <0.001 | |||
| HPV-18 related (no HPV-16) |
1.33 (0.76−2.31) | 0.305 | 1.40 (0.80−2.46) | 0.296 | 0.92 (0.37−2.29) | 0.864 | |||