Fig. 4.

Upregulation of HADHA alleviated hepatic steatosis and inflammation in NAFLD mice. NAFLD mice were fed a HFD for 8 weeks, and Adv-NC or Adv-HADHA was used for tail vein injection once 2 weeks before sacrifice. A: TG, TC, ALT and AST in NAFLD mouse serum were examined by biochemical tests. B: An Oil Red O staining assay detected the accumulation of lipid droplets in mouse liver tissues (400×). C: An HE staining assay was used to analyse the liver tissue lesions of mice (400×). *P < 0.05 compared with the control group; #P < 0.05 compared with the HFD + Adv-NC group