Table 4.
.Percentage of sperm abnormalities induced in male mice after treatment with vinblastine
| Experimental groups and doses | Total abnormal sperm | No. and (%)of different types of sperm abnormalities | |||||
|---|---|---|---|---|---|---|---|
| Head abnormalities | Tail abnormalities | ||||||
| No. | Mean (%) ± SE | Amorphous | Without hook | Triangle | Banana | Coiled tail | |
| I-Control (−ve) | 152 | 3.04 ± 0.19a | 16(0.32) | 4(0.08) | 2(0.04) | 1(0.02) | 20(0.40) |
| II-Vinblastine 3 mg/kg | 472 | 9.44 ± 0.13b | 71(1.42) | 69(1.38) | 18(0.36) | 23(0.46) | 291(5.82) |
| 4.5 mg/kg | 520 | 10.40 ± 0.73b,c | 85(1.70) | 67(1.34) | 19(0.38) | 19(0.38) | 330(6.60) |
| 6 mg/kg | 553 | 11.06 ± 0.14c | 54(1.08) | 87(1.74) | 18(0.36) | 11(0.22) | 383(7.66) |
Total number of examined sperms 5000 per each treatment (1000/mouse, five mice/group).One way ANOVA–Tukey’s multiple comparisons test was used. The values having different superscript letters in each column are significantly different from one another at p < 0.05