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. 2022 Sep 6;33(2):925–935. doi: 10.1007/s00330-022-09101-x

Fig. 2.

Fig. 2

Evaluation of the stability of the progression markers. a The pattern example among the top 4 ranked pattern. b Most informative progression markers identified by the model, and the repeatability of this ranking after 20 runs of random 95–5% patient splits. The top 4 ranked patterns are stable across all runs. The ranking of less informative patterns fluctuates across runs. c The top 4 ranked cluster volume representation from a patient at 4 different time points