Table 1.
Clinicopathological parameters of 175 patients with resected pancreatic ductal adenocarcinoma associated with epithelial and stromal gp130 expression
| Characteristics | n | gp130 expression* (%) | |||
|---|---|---|---|---|---|
| 175 | Epithelial | p | Stromal | p | |
| Age | |||||
| ≤ 60 years | 42 | 80.5 | 0.765 | 9.8 | 1.000 |
| > 60 years | 133 | 78.3 | 9.3 | ||
| Sex | |||||
| Male | 94 | 79.3 | 0.856 | 9.8 | 0.857 |
| Female | 81 | 78.2 | 9.0 | ||
| Tumor infiltration | |||||
| T1-2 | 17 | 87.5 | 0.527 | 6.3 | 1.000 |
| T3-4 | 158 | 77.9 | 9.7 | ||
| Lymph node status | |||||
| N0 | 63 | 78.7 | 0.974 | 8.2 | 0.685 |
| N1 | 112 | 78.9 | 10.1 | ||
| Metastasis | |||||
| M0 | 160 | 78.7 | 1.000 | 9.7 | 1.000 |
| M1 | 15 | 80.0 | 6.7 | ||
| Staging | |||||
| 0-IIa | 54 | 76.9 | 0.687 | 9.6 | 0.952 |
| IIb-IV | 121 | 79.7 | 9.3 | ||
| Grading | |||||
| G1-2 | 58 | 83.6 | 0.288 | 7.3 | 0.587 |
| G3 | 117 | 76.5 | 10.4 | ||
| Residual tumor | |||||
| R0 | 97 | 71.6 | 0.015 | 9.5 | 0.820 |
| R1 | 74 | 87.3 | 8.5 | ||
| Chemotherapy | |||||
| No | 38 | 83.8 | 0.404 | 8.1 | 1.000 |
| CTx | 137 | 77.4 | 9.8 | ||
| Radiochemotherapy | |||||
| No | 96 | 77.7 | 0.680 | 9.6 | 0.936 |
| RCTx | 79 | 80.3 | 9.2 | ||
CTx chemotherapy, RCTx Radiochemotherapy
*gp130 expression includes following immunohistological staining scores: 1 (weak), 2 (moderate) or 3 (strongly positive); Staging according to UICC 2010