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. 2023 Jan 18;14:1081612. doi: 10.3389/fphar.2023.1081612

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Copyright © 2023 Wu, Zhang, Liu, Wei, Li, Ma, Wang, Zhu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The PDA-TMZ NPs gathered in the cytoplasm of U87 cells. (B) The Pep-1@PDA-TMZ NPs were endocytosed by the nucleus of U87 cells (green fluorescence).