Table 1.

Role of exosomes from different cell sources in the tumor microenvironment.

Source of exosomes	Material	Object	Role	Reference
CD8+T cells	mRNA, miRNA	Malignant tumor	Affects tumor development	(98)
	miR-765/PLP2	UCEC	Inhibition of estrogen to promote UCEC	(99)
CD4+T cells	FasL	T cells	Induced T cell apoptosis and immune disorders	(100)
	miRNA-150	Lymphoid tissue	Serum markers	(101)
B cells	DC vaccine	T cells	Inhibition of immune suppressive cytokine production	(102)
NK cells	Perforin Fas/FasL	Tumor cells	Cytotoxicity, tumor cell apoptosis	(103)
	Immune components	Tumor cells	Immunomodulatory, reverse tumor immune suppression	(104)
DCs	MHC I, MHCII	TME	The immune response is dysfunctional	(105)
Neutrophil granulocyte	Cytotoxic protein	Tumor cells	Induction of apoptosis	(106)
	Adriamycin	Glioma	No limitations, promising treatments	(107)
Macrophages	miRNA	Ovarian cancer	Immune suppression, promote cancer development	(108)
	miR-193a-5p	Tumor cells	Promote tumor invasion	(109)
	IncRNA	Cancer cells	Aerobic glycolysis, anti-apoptosis ability of cells	(110)
Mast cells	KIF protein	Tumor	Promote cancer cell proliferation	(111)

UCEC, Endometrial cancer.