TABLE 4.
Clinical, laboratory, and combined multivariable regression models for factors associated with mortality in 230 critically ill calves
| Variable | Mortality | OR | 95% CI | P‐value | Se (%) | Sp (%) | Acc (%) | |
|---|---|---|---|---|---|---|---|---|
| Clinical model | ||||||||
| n = 116 | Gender (male) | 70.3% (45/64) | 4.3 | 1.5‐11.9 | .01 | 85.9 | 66.7 | 78.4 |
| Temperature (/°C increase) | 0.55 | 0.36‐0.85 | .01 | |||||
| Color mucosae (pale) | 84.4% (27/32) | 7.1 | 1.9‐26.2 | .003 | ||||
| Abnormal behavior | 77.1% (54/70) | 3.3 | 1.3‐8.5 | .01 | ||||
| Laboratory model | ||||||||
| Model A | Blood culture positive | 79.3% (46/58) | 3.3 | 1.6‐7.0 | .002 | 60.6 | 71.0 | 64.6 |
| n = 178 | Acidosis (≤7.18) | 78.7% (37/47) | 2.9 | 1.3‐6.4 | .01 | |||
| Model B | Hypoglycemia (≤55 mg/dL) | 87.5% (35/40) | 5.2 | 1.9‐14.4 | .001 | 54.3 | 84.1 | 65.5 |
| n = 168 | Acidosis (≤7.18) | 78.7% (37/47) | 3.5 | 1.4‐8.8 | .01 | |||
| Combined (clinical + laboratory) model | ||||||||
| Model A | Abnormal behavior | 75.0% (48/64) | 3.3 | 1.1‐10.0 | .03 | 85.7 | 73.2 | 80.8 |
| n = 104 | Gender (male) | 68.3% (41/60) | 4.3 | 1.4‐13.2 | .01 | |||
| Tachycardia (>126 bpm) | 67.4% (29/43) | 3.4 | 1.1‐10.8 | .04 | ||||
| Color mucosae (pale) | 84.6% (22/26) | 10.4 | 2.5‐43.7 | .001 | ||||
| Acidosis (≤7.18) | 86.2% (25/29) | 5.3 | 1.3‐21.9 | .02 | ||||
| Blood culture positive | 80.0% (28/35) | 6.9 | 1.9‐25.0 | .003 | ||||
| Model B | Abnormal behavior | 73.1% (49/67) | 3.1 | 1.2‐8.0 | .02 | 78.6 | 70.3 | 73.6 |
| n = 106 | Tachycardia (>126 bpm) | 69.0% (29/42) | 2.7 | 1.0‐7.2 | .05 | |||
| Acidosis (≤7.18) | 85.7% (24/28) | 4.2 | 1.2‐15.0 | .03 | ||||
| Hypoglycemia (≤55 mg/dL) | 92.0% (23/25) | 10.4 | 2.1‐51.5 | .004 | ||||
Note: Abnormal behavior included an apathic state, decubitus, and/or neurological signs.
Abbreviations: 95% CI, 95% confidence interval; Acc, accuracy; n, calves in model; N, calves with variable present; OR, odds ratio; Se, sensitivity; Sp, specificity.