TABLE 7.
Theoretical inappropriateness per antimicrobial for the isolated bacteria of 79 blood cultures of critically ill calves
| Antimicrobial (number isolates with known susceptibility) | Acquired resistance % (number) | Intrinsic resistance % (number) | Unclear mechanism % (number) | Inappropriate treatment a % (number) |
|---|---|---|---|---|
| Penicillin (57) | 20.4 (10) | 79.6 (39) | / | 86.0 (49) |
| Ampicillin/amoxicillin (60) | 82.5 (33) | 17.5 (7) | / | 66.7 (40) |
| Amoxicillin + clav. acid (52) | 89.5 (17) | 10.5 (2) | / | 36.5 (19) |
| Cefalexin (52) | 56.0 (14) | 40.0 (10) | 4.0 (1) | 48.1 (25) |
| Ceftiofur (56) | 88.2 (15) | 5.9 (1) | 5.9 (1) | 30.4 (17) |
| Cefquinome (56) | 87.5 (14) | 6.3 (1) | 6.3 (1) | 28.6 (16) |
| Macrolides (52) | 14.0 (6) | 86.0 (37) | / | 82.7 (43) |
| Lincosamides (49) | 21.3 (10) | 78.7 (37) | / | 95.9 (47) |
| Florfenicol (46) | 100 (14) | / | / | 30.4 (14) |
| Spectinomycin (39) | 46.2 (6) | 53.8 (7) | / | 33.3 (13) |
| Gentamicin (43) | 66.7 (14) | 33.3 (7) | / | 48.8 (21) |
| Flumequine (42) | 75.0 (12) | 25.0 (4) | / | 38.1 (16) |
| Enrofloxacin (56) | 100 (11) | / | / | 19.6 (11) |
| Tetracycline (57) | 97.4 (38) | 2.6 (1) | / | 68.4 (39) |
| Doxycycline (56) | 100 (31) | / | / | 55.4 (31) |
| Potentiated sulphonamides (59) | 100 (30) | / | / | 50.8 (30) |
a
Appropriateness based on antimicrobial sensitivity results and intrinsic resistance, displaying whether the antimicrobial would have been appropriate if therapy was initialized with that particular drug.