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. 2022 Dec 15;16(1):11–28. doi: 10.1159/000528083

Table 5.

Potential updates in the MNT for adult obesity guidelines based on the latest evidence

Current guideline Impact of new evidence
Partial meal replacements (replacing one to two meals/day as part of a calorie-restricted intervention) to reduce BW, WC, BP and improve glycaemic control
Level 1a, grade B
New evidence in support of the guideline in both Level 2 (n = 3) and level 1 (n = 2)
Evidence level to remain unchanged
Strength of recommendation could be upgraded to grade A

Intermittent or continuous calorie restriction achieved similar short-term BW reduction
Level 2a, grade B
New evidence includes both level 2 (n = 2) and level 1 (n = 5)
New level 1 evidence indicates potential superiority of fasting approaches on weight outcomes and lipid profiles, but it is currently inconclusive
No evidence to support a superiority in glucose metabolism Closer follow-up of the literature may warrant recommendation update in the near future