Table 2.
Lipoparticle-associated apoE distribution in VLDL, LDL and HDL fractions.
| Mouse model | Sex | % apoE in the VLDL fraction | % apoE in the LDL fraction | % apoE in the HDL fraction | apoE ratio in LDL/HDL fractions |
|---|---|---|---|---|---|
| E3-HL | Male | 16 | 22 | 62 | 0.35 |
| Female | 14 | 48 | 38 | 1.28 | |
| E3-TR | Male | 11 | 31 | 58 | 0.54 |
| Female | 10 | 28 | 62 | 0.45 |
E3-HL APOE ε3/ε3 humanized liver mice, E3-TR APOE ε3/ε3 targeted replacement mice, VLDL very low density lipoprotein, LDL low density lipoprotein, HDL high density lipoprotein, apoE apolipoprotein E.