Table 4.

The ratio of delirium occurrence in lipophilic and hydrophilic statin groups before and after inverse probability of treatment weighting

APACHE group	Variable	Cohort before Inverse probability of treatment weighting					Cohort after Inverse probability of treatment weighting
		All	Lipophilic	Hydrophilic	p value		All	Lipophilic	Hydrophilic	p value
1	Patients (n)	59	41	18			36.0	18.0	18
	Age	64.3 ± 14.9	62.0 ± 15.4	69.5 ± 12.8	0.074		69.4 ± 1.8	69.4 ± 2.0	69.5 ± 3.0	0.972
	Male	43 (72.88)	30 (73.17)	13 (72.22)	> 0.999		26.12 (72.55)	13.12 (72.88)	13.00 (72.22)	0.960
	Delirium	13 (22.0)	10 (24.4)	3 (16.7)	0.735		7.4 (20.5)	4.4 (24.3)	3.0 (16.7)	0.526
2	Patients (n)	196	143	53			106.0	53.0	53
	Age	76. 5 ± 11.3	76.3 ± 12.0	76.9 ± 9.3	0.728		76.9 ± 0.8	76.9 ± 0.9	76.9 ± 1.3	0.978
	Male	120 (61.2)	83 (58.0)	37 (69.8)	0.133		73.9 (69.7)	36.9 (69.6)	37.0 (69.8)	0.980
	Delirium	80 (40.8)	56 (39.2)	24 (45.3)	0.439		44.3 (41.8)	20.3 (38.3)	24.0 (45.3)	0.378
3	Patients (n)	154	125	29			58.0	29.0	29
	Age	76.3 ± 12.1	76.7 ± 11.8	74.4 ± 13.4	0.349		74.5 ± 1.4	74.6 ± 1.3	74.4 ± 2.5	0.936
	Male	90 (58.4)	69 (55.2)	21 (72.4)	0.090		41.9 (72.3)	20.9 (72.2)	21.0 (72.4)	0.980
	Delirium	84 (54.6)	69 (55.2)	15 (51.7)	0.735		29.7 (51.2)	14.7 (50.6)	15.0 (51.7)	0.916
4	Patients (n)	45	36	9			18.0	9.0	9
	Age	77.3 ± 10.5	76.7 ± 10.7	79.7 ± 9.8	0.450		79.7 ± 1.8	79.8 ± 1.7	79.7 ± 3.3	0.967
	Male	26 (57.8)	20 (55.6)	6 (66.7)	0.712		12.1 (66.8)	6.1 (67.0)	6.0 (66.7)	0.985
	Delirium	34 (75.6)	28 (77.8)	6 (66.7)	0.666		13.4 (74.1)	7.4 (81.5)	6.0 (66.7)	0.329

Cohort before: Values are presented as mean ± standard deviation or number (%). Cohort after: Values are presented as weighted mean ± standard error or weighted number (%).

APACHE II, Acute Physiology and Chronic Health Evaluation-II.