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Low level of FSP1 in B-acute lymphoblastic leukemia contributes to ferroptosis sensitivity. (A) FSP1 protein level comparison between GPX4-sensitive and non-sensitive CCLE cell lines by cancer type (see material and methods). (B) FSP1 western blot on parental vs. FSP1 over-expressing B-acute lymphoblastic leukemia (B-ALL) cells. (β-actin is shown as a loading control. (C) RSL3 dose-response curves in B-ALL pools overexpressing high or low levels of FPS1. Conc: concentration.
