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. 2022 Sep 22;108(2):382–393. doi: 10.3324/haematol.2022.280786

Figure 6.

Figure 6.

Integration of GPX4-related pathways. Several genes/pathways found essential in acute lymphoblastic leukemia (ALL) cells potentially regulate GPX4 activity which may explain their acute vulnerability to ferroptosis induction. Genes in bold characters are found within the 319 ALL-enriched essential genes.