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. 2023 Jan 18;11:1103923. doi: 10.3389/fcell.2023.1103923

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Copyright © 2023 Li, Luo, Li, Liu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phylogenetic analyses of insect Ilp8s. (A) Cladogram shows that orthologs of Ilp8s are found in major groups of insects (red dots) except for the lepidopterans and coleopterans (white dots). (B) Phylogenetic tree of Ilps in D. melanogaster, D. mercatorum and B. dorsalis. The Ilp8 cluster is well separated from the other fly Ilps. The neighbor-joining tree was generated using MEGA 7.0 with 1,000 bootstrap test. Bootstrap values are indicated at each branch. The scale bar represents the branch length.