Table 1.
Inhibitory activities of tinengotinib on human kinases.
| Kinase | IC50/nmol/L | Kinase | IC50/nmol/L |
|---|---|---|---|
| Aurora A | 1.2 | KDR | 2.5 |
| Aurora B | 3.3 | VEGFR3 | 0.93 |
| FGFR1 | 2.3 | JAK1 | 15 |
| FGFR2 | 1.5 | JAK2 | 0.75 |
| FGFR3 | 3.5 | CSF1R | 7.0 |
| VEGFR1 | 2.4 |
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