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. 2022 Nov 17;29(3):592–601. doi: 10.1158/1078-0432.CCR-22-0921

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 6. Time-dependent ROC curves at 12 months WW time. These figures show the discriminating value of the IMDC criteria together with the number of organ sites (the two variables underlying the “W&W criteria”) and gm [18F]FDG SUVmax (A) and [89Zr]Zr-DFO-girentuximab (B), respectively, individually and when combined. All variables were evaluated continuously, and for the curves that show the combined discriminating value of variables, we used Firth penalized Cox regression to obtain a combined prognostic score. — Time-dependent ROC curves at 12 months WW time. These figures show the discriminating value of the IMDC criteria together with the number of organ sites (the two variables underlying the “W&W criteria”) and gm [¹⁸F]FDG SUVmax (A) and [⁸⁹Zr]Zr-DFO-girentuximab (B), respectively, individually and when combined. All variables were evaluated continuously, and for the curves that show the combined discriminating value of variables, we used Firth penalized Cox regression to obtain a combined prognostic score.