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. 2022 Mar 3;191(7):1202–1211. doi: 10.1093/aje/kwac040

Table 2.

Hazard Ratiosa for Incident Dementia by 2017 Associated With Dietary Copper Intake (n = 10,250) in the Atherosclerosis Risk in Communities Study, United States

Overall With High SaturatedFat Intake With Non-High Saturated Fat Intake
Type of Copper HR 95% CI HR 95% CI HR 95% CI
Total copper 1.17 0.89, 1.45 1.50 1.00, 2.00 1.05 0.78, 1.33
Copper from food 1.20 0.92, 1.48 1.49 1.04, 1.95 1.08 0.81, 1.36
Copper from supplements 0.98 0.91, 1.04 1.01 0.85, 1.16 0.97 0.90, 1.05

Abbreviations: CI, confidence interval; HR, hazard ratio.

a Models adjusted for age, sex, race-center, apolipoprotein E ε4 allele, education, body mass index, smoking, alcohol consumption, total calorie intake, saturated fat intake, zinc intake, iron intake, and dietary patterns. P for interaction between copper from food and high saturated fat is 0.03; P for interaction between copper from supplements and high saturated fat is 0.68; and P for interaction between total copper and high saturated fat is 0.03.