Table 1.
Clinical and Demographic Characteristics of Ulcerative Colitis and Crohn’s Disease Patients Grouped by Patient-Reported Disease Activity at Study Enrollment
| Ulcerative Colitis (n = 23) | P Value | Crohn’s Disease (n = 70) | P Value | |||
|---|---|---|---|---|---|---|
| Patient-Reported Active (n = 9 [39%]) | Patient-Reported Nonactive (n = 14 [61%]) | Patient-Reported Active (n = 21 [30%]) | Patient-Reported Nonactive (n = 49 [70%]) | |||
| Increased stool frequency | 6 (67) | 0 (0%) | 18 (86) | 0(0) | ||
| Abdominal pain | 1 (11) | 0 (0) | 8 (38) | 0(0) | ||
| Rectal bleeding | 7 (78) | 0 (0) | 11 (52) | 3 (6) | ||
| Mucosal healing (fecal calprotectin ≤100 µg/g) | 1 (11) | 5 (36) | .34 | |||
| Mucosal healing (fecal calprotectin ≤250 µg/g | 12 (57) | 29 (59) | 1.0 | |||
| Fecal calprotectin, µg/g | 364 (104-825) | 141 (92-629) | .4 | 204 (90-484) | 128 (83-393) | .62 |
| Disease location | ||||||
| Left side | 2 (22) | 3 (21) | 1.0 | |||
| Pancolitis | 7 (78) | 11 (79) | ||||
| Ileal | 0 (0) | 8 (16) | .38 | |||
| Ileocolonic | 20 (95) | 34 (69) | ||||
| Colon only | 1 (5) | 7 (14) | ||||
| Age at sample collection, y | 16.05 (15.24-16.56) | 15.05 (12.84-17.14) | .82 | 15.7 (13.2-17.3) | 13.9 (12.4-15.8) | .10 |
| Male | 5 (56) | 10 (71) | .66 | 10 (48) | 32 (65) | .19 |
| Caucasian | 8 (89) | 14 (100) | .39 | 19 (90) | 44 (90) | 1.0 |
| Disease duration, y | 2.5 (0.5-3.7) | 1.8 (0.8-4.2) | .73 | 2.1 (0.5-4.7) | 3.1 (1.4-6.3) | .08 |
| IBD medication | ||||||
| On biologic | 3 (33) | 7 (50) | .67 | 13 (62) | 35 (71) | .58 |
| Antibiotic within 60 d | 2 (22) | 2 (14) | 1.0 | 3 (14) | 5 (10) | .69 |
| History of surgery | 2 (10) | 11 (22) | .32 | |||
Values are n (%) or median (interquartile range).
Abbreviation: IBD, inflammatory bowel disease.