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. 2022 Dec 9;42(3):e111065. doi: 10.15252/embj.2022111065

Figure EV3. Conservation of ABCA and ABCG family structural elements.

Figure EV3

  1. Ribbon representation of select ABCG family transporter structures and their respective PDB IDs including apo open ABCG2 (red), closed ATP‐bound structure of ABCG2EQ (black), and ABCG5/G8 (blue and green, respectively).
  2. Alignment of NBD‐TMD pairs from open and closed conformations of ABCG2 (left), ABCG2 and ABCG5/G8 (center), and closed ABCG2 with TMD‐NBD pairs from ABCA7 half 1 (gold) and half 2 (orange) along with the root mean square deviations (RMSD) of aligned atoms shown at the bottom.