Table 2.

Distribution of concomitant diagnoses among young people with HF

Diagnostic		Men				Women				All genders n = 70 075	P-value IHD in Men vs. Women
		Myo-cardio n = 11 349	IHD n = 16 855	Others n = 17 755	All aetiologies n = 45 959	Myo-Cardio n = 5038	IHD n = 4719	Others n = 14 359	All aetiologies n = 24 116
Lifestyle habits	Alcoholism, n (%)	2666 [23.5 (22.7; 24.3)]	3060 [18.2 (17.6; 18.8)]	3774 [21.3 (20.7; 21.9)]	9500 [20.7 (20.3, 21)]	342 [6.8 (6.1; 7.5)]	411 [8.7 (7.9; 9.6)]	1233 [8.6 (8.1; 9.1)]	1986 [8.2 (7.9, 8.6)]	11486 [16.4 (16.1; 16.7)]	< 0.001
	Smoking, n (%)	3651 [32.2 (31.3; 33.0)]	8908 [52.9 (52.1; 53.6)]	4934 [27.8 (27.1; 28.5)]	17493 [38.1 (37.6, 38.5)]	1026 [20.4 (19.3; 21.5)]	2111 [44.7 (43.3; 46.2)]	2657 [18.5 (17.9; 19.2)]	5794 [24.0 (23.5, 24.6)]	23287 [33.2 (32.9; 33.6)]	< 0.001
	Drug use, n (%)	242 [2.1 (1.9; 2.4)]	354 [2.1 (1.9; 2.3)]	671 [3.8 (3.5; 4.1)]	1267 [2.8 (2.6, 2.9)]	49 [1,0 (0.7; 1.3)]	75 [1.6 (1.3; 2.0)]	244 [1.7 (1.5; 1.9)]	368 [1.5 (1.4, 1.7)]	1635 [2.3 (2.2; 2.4)]	0.031
Cardio-vascular risk factors	Arterial hypertension, n (%)	3279 [28.9 (28.1; 29.7)]	6407 [38.0 (37.3; 38.8)]	5313 [29.9 (29.3; 30.6)]	14999 [32.6 (32.2, 33.1)]	1533 [30.4 (29.2; 31.7)]	1995 [42.3 (40.9; 43.7)]	4040 [28.1 (27.4; 28.9)]	7568 [31.4 (30.8, 32.0)]	22567 [32.2 (31.9; 32.6)]	< 0.001
	Gestational hypertension, n (%)	0.00	0.00	0.00	0.00	362 [7.2 (6.5; 7.9)]	166 [3.5 (3.0; 4.1)]	1072 [7.5 (7.0; 7.9)]	1600 [6.6 (6.3, 7.0)]	-	-
	Obesity, n (%)	2560 [22.6 (21.8; 23.3)]	4478 [26.6 (25.9; 27.2)]	3454 [19.5 (18.9; 20.1)]	10492 [22.8 (22.4, 23.2)]	1266 [25.1 (23.9; 26.4)]	1489 [31.6 (30.2; 32.9)]	3602 [25.1 (24.4; 25.8)]	6357 [26.4 (25.8, 26.9)]	16849 [24.0 (23.7; 24.4)]	< 0.001
	Diabetes type 1, n (%)	302 [2.7 (2.4; 3.0)]	1111 [6.6 (6.2; 7.0)]	781 [4.4 (4.1; 4.7)]	2194 [4.8 (4.6, 5.0)]	178 [3.5 (3.1; 4.1)]	517 [11.0 (10.1; 11.9)]	789 [5.5 (5.1; 5.9)]	1484 [6.2 (5.9, 6.5)]	3678 [5.2 (5.1; 5.4)]	< 0.001
	Diabetes type 2, n (%)	1038 [9.2 (8.6; 9.7)]	3227 [19.2 (18.6; 19.8)]	1841 [10.4 (9.9; 10.8)]	6106 [13.3 (13.0, 13.6)]	495 [9.8 (9.0; 10.7)]	1034 [21.9 (20.7; 23.1)]	1566 [10.9 (10.4; 11.4)]	3095 [12.8 (12.4, 13.3)]	9201 [13.1 (12.9; 13.4)]	< 0.001
	Dyslipidaemia, n (%)	1001 [8.8 (8.3; 9.4)]	5289 [31.4 (30.7; 32.1)]	1499 [8.4 (8.0; 8.9)]	7789 [16.9 (16.6, 17.3)]	387 [7.7 (7.0; 8.5)]	1194 [25.3 (24.1; 26.6)]	970 [6.8 (6.4; 7.2)]	2551 [10.6 (10.2, 11.0)]	10340 [14.8 (14.5; 15.0)]	< 0.001
	Chronic renal failure, n (%)	913 [8.0 (7.6; 8.6)]	1391 [8.3 (7.8; 8.7)]	2124 [12.0 (11.5; 12.5)]	4428 [9.6 (9.4, 9.9)]	440 [8.7 (8.0; 9.6)]	568 [12.0 (11.1; 13.0)]	1640 [11.4 (10.9; 12.0)]	2648 [11.0 (10.6, 11.4)]	7076 [10.1 (9.9; 10.3)]	< 0.001
	Sleep apnoea, n (%)	823 [7.3 (6.8; 7.8)]	1262 [7.5 (7.1; 7.9)]	1375 [7.7 (7.4; 8.2)]	3460 [7.5 (7.3, 7.8)]	197 [3.9 (3.4; 4.5)]	275 [5.8 (5.2; 6.5)]	758 [5.3 (4.9; 5.7)]	1230 [5.1 (4.8, 5.4)]	4690 [6.7 (6.5; 6.9)]	< 0.001
Other cardiac diagnosis	Arrhythmia, n (%)	4241 [37.4 (36.5; 38.3)]	4995 [29.6 (29.0; 30.3)]	4940 [27.8 (27.2; 28.5)]	14176 [30.8 (30.4, 31.3)]	1400 [27.8 (26.6; 29.1)]	1209 [25.6 (24.4; 26.9)]	2853 [19.9 (19.2; 20.5)]	5462 [22.6 (22.1, 23.2)]	19638 [28.0 (27.7; 28.4)]	< 0.001
	Pulmonary embolism, n (%)	388 [3.4 (3.1; 3.8)]	373 [2.2 (2.0; 2.5)]	987 [5.6 (5.2; 5.9)]	1748 (3.8 (3.6, 4.0)]	196 [3.9 (3.4; 4.5)]	161 [3.4 (2.9; 4.0)]	992 [6.9 (6.5; 7.3)]	1349 [5.6 (5.3, 5.9)]	3097 [4.4 (4.3; 4.6)]	< 0.001
	Primary pulmonary hypertension, n (%)	370 [3.3 (2.9; 3.6)]	311 [1.9 (1.7; 2.1)]	709 [4.0 (3.7; 4.3)]	1390 [3.0 (2.9, 3.2)]	229 [4.6 (4.0; 5.2)]	144 [3.1 (2.6; 3.6)]	928 [6.45 (6.1; 6.9)]	1301 [5.4 (5.1, 5.7)]	2691 [3.8 (3.7; 4.0)]	< 0.001
	Endocarditis, n (%)	139 [1.2 (1.0; 1.5)]	201 [1.2 (1.0; 1.4)]	860 [4.8 (4.5; 5.2)]	1200 [2.6 (2.5, 2.8)]	61 [1.2 (0.9; 1.6)]	70 [1.5 (1.2; 1.9)]	373 [2.6 (2.4; 2.9)]	504 [2.1 (1.9, 2.3)]	1704 [2.4 (2.3; 2.5)]	0.131
Other extra cardiac	Cancer, n (%)	996 [8.8 (8.3; 9.3)]	1717 [10.2 (9.7; 10.7)]	2883 [16.2 (15.7; 16.8)]	5596 [12.2 (11.9, 12.5)]	941 [18.7 (17.6; 19.8)]	803 [17.0 (16.0; 18.1)]	3512 [24.5 (23.8; 25.2)]	5256 [21.8 (21.3, 22.3)]	10852 [15.5 (15.2; 15.8)]	< 0.001
	Cushing’s syndrome, n (%)	8 [0.07 (0.03; 0.1)]	14 [0.1 [0.1; 0.1)]	37 [0.2 (0.2; 0.9)]	59 [0.1 (0.1, 0.2)]	15 [0.3 (0.2; 0.5)]	24 [0.5 (0.3; 0.8)]	58 [0.4 (0.3; 0.5)]	97 [0.4 (0.3, 0.5)]	156 [0.2 (0.2; 0.3)]	< 0.001
	Hyper-aldosteronis, n (%)	27 [0.2 (0.2; 0.4)]	23 [0.1 (0.1; 0.2)]	44 [0.3 (0.2; 0.3)]	94 [0.2 (0.2, 0.3)]	19 [0.4 (0.2; 0.6)]	18 [0.4 (0.2; 0.6)]	50 [0.4 (0.3; 0.5)]	87 [0.4 (0.3, 0.4)]	181 [0.3 (0.2; 0.3)]	< 0.002
	Adrenal gland, diseases, n (%)	58 [0.5 (0.4; 0.7)]	66 [0.4 (0.3; 0.5)]	129 [0.7 (0.6; 0.9)]	253 [0.6 (0.5, 0.6)]	40 [0.8 (0.6; 1.1)]	54 [1.1 (0.9; 1.5)]	154 [1.1 (0.9; 1.3)]	248 [1.0 (0.9, 1.2)]	501 [0.7 (0.7; 0.8)]	< 0.001