Table 3.

History of signs and symptoms associated with death and survival (N=1521)

				Univariableb			Multivariablec
	Na	Survival N (%)	Death N (%)	OR	95% CI	p	aOR	95% CI	p
Total	1521	1484	37
Fever duration, median (IQR), d	1509	5 (3–7)	5 (4–7)	0.99	0.91 to 1.07	NS
Symptom duration, median (IQR), d	1453	4 (3–4)	4 (3–4)	1.19	0.84 to 1.68	NS
History of signs and symptoms
Altered consciousness	1515	62 (4)	21 (57)	30.00	14.91 to 60.26	<0.0001	21.68	8.72 to 53.92	<0.0001
Bleedingd	1517	32 (2)	7 (19)	10.59	4.33 to 25.89	<0.0001	14.08	4.21 to 47.13	<0.0001
Oliguria	1515	67 (5)	12 (32)	10.11	4.87 to 21.00	<0.0001	3.41	1.21 to 9.61	0.020
Breathlessness	1484	190 (13)	17 (47)	5.92	3.03 to 11.60	<0.0001	2.91	1.24 to 6.87	0.015
Seizures	1514	26 (2)	6 (17)	11.17	4.28 to 29.13	<0.0001	2.13	0.62 to 7.38	NS
Jaundice	1488	91 (6)	9 (24)	4.80	2.20 to 10.48	<0.0001	1.69	0.61 to 4.70	NS
Prostration	1507	343 (23)	16 (46)	2.78	1.41 to 5.45	0.003	0.63	0.26 to 1.55	NS
Vomiting	1492	494 (34)	19 (51)	2.05	1.07 to 3.95	0.031	1.82	0.80 to 4.14	NS
Nausea	1485	514 (36)	18 (49)	1.72	0.90 to 3.31	NS
Myalgia	1516	493 (33)	18 (49)	1.90	0.99 to 3.64	NS
Cough	1518	489 (33)	10 (27)	0.75	0.36 to 1.57	NS
Sputum	1516	181 (12)	5 (14)	0.82	0.34 to 2.32	NS
Headache	1517	816 (55)	21 (57)	1.07	0.55 to 2.06	NS
Retro orbital pain	1514	151 (10)	2 (6)	0.52	0.12 to 2.17	NS
Abdominal pain	1485	292 (20)	6 (17)	0.79	0.33 to 1.92	NS
Diarrhea	1486	225 (16)	5 (14)	0.88	0.34 to 2.28	NS
Arthralgia	1515	210 (14)	6 (16)	1.17	0.48 to 2.84	NS
Rash	1515	33 (2)	1 (3)	1.22	0.16 to 9.14	NS

Abbreviations: aOR, adjusted odds ratio; NS, not significant.

^aTotal number investigated among 1521 patients. Discrepancies due to missing values.

^bUnivariable logistic regression.

^cMultivariable logistic regression, age and gender were included.

^dMerged variables “Abnormal bleeding” (N survival and death=19 and 4) and “Blood in stools” (N=16 and 5).

Missing coded as negative in merged variables for the sake of the analyses.