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. 2022 Sep 20;117(2):91–101. doi: 10.1093/trstmh/trac091

Table 6.

Duration of hospitalization and antimicrobial treatment associated with microbiological diagnoses among patients who died (n=37)

Died
Total Na Survived Total died P . f. P . v. P. f + lepto-spirosis Lepto-spirosis Bacteremiab Scrub typhus Scrub and lepto-spirosis Scrub and dengue Dengue No microbiol. diagnosis
Total, N 1521 1484 37 2 3 2 1 2 3c 1 2 2 19
Duration in hospital, median (IQR), dd 1270 4 (3–5) 3 (1–4)
Antimalarials, n (%)
  Artemisinine and/or quinine 2 3 2
  Artesunate 233 215 (92) 18 (8) 3 1 1 1 1 11
  Artemether 31 26 (84) 5 (16) 2 1 2
  Quinine 21 15 (71) 6 (29) 2 1 3
  Chloroquine 93 87 (94) 6 (7) 2 1 3
  Primaquine 50 49 (98) 1 (2) 1
  Mefloquine 6 4 (67) 2 (33) 2
  Sulphadox/pyrimeth 4 3 (75) 1 (25) 1 1 1 1
Antibiotics, n (%)
 3. gen cephalosporin 971 944 (97) 27 (3) 2 1 1 2 1 1 1 17
 2. gen cephalosporin 38 37 (97) 1 (3) 1
 1. gen cephalosporin 27 26 (96) 1 (4) 1
 Carbapenem 6 6 (100) 0
 Penicillin 117 105 (90) 12 (10) 2 1 1 1 7
 Aminoglycoside 71 63 (89) 8 (11) 2 1 1 4
 Piperacillin/tazobactam 54 49 (91) 5 (9) 1 2 2
 Quinolone 62 60 (97) 2 (3) 1 1
 Macrolide 123 122 (99) 1 (1) 1
 Tetracycline 609 586 (92) 23 (4) 2 1 1 1 3 1 2 12
 Clindamycin 3 2 1 1
a

Total number investigated among 1521 patients. Discrepancies due to missing values.

b

S. aureus case had received three antibiotics and E. coli case no antibiotics.

c

One patient was Scrub ELISA positive and IFA negative, but diagnosis confirmed by eschar.

d

9/32 (28%) died day 1, 6/32 day 2 and 7/32 day 3. Mann Whitney U test p=0.001.