Fig. 1.

Schematic showing the postprocessing to calculate brain structure-wise T₁, T₂, cortical thickness, and subcortical volume values from 3D MRF maps. MRF-derived T₁ maps are postprocessed voxel-wise to generate synthetic T₁-weighted images (left). These MRF-derived T₁-weighted images are imported into the automated brain parcellation software to generate subject-specific neuroanatomical parcellation (bottom). These subject-specific parcellation masks are directly applied to the T₁ and T₂ maps to obtain median relaxation times for each corresponding neuroanatomical region (top).