Table 7.
Sensitivity, Specificity, Positive Predictive Value, and Negative Predictive Value for the T2Candida and Platelia Candida Antigen Plus Results Used in Combination
| Sensitivity | Specificity | Positive Predictive Value | Negative Predictive Value | Specimens Exceeding Cutoff | |
|---|---|---|---|---|---|
| Test | % (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | n |
| T2Candida only | 77.3 (54.6, 92.2) | 97.2 (95.1, 98.6) | 60.7 (40.6, 78.5) | 98.7 (97.0, 99.6) | 28 |
| Platelia Candida Antigen Plus only | 40.9 (20.7, 63.7) | 97.2 (95.1, 98.6) | 45.0 (23.1, 68.5) | 96.7 (94.5, 98.3) | 20 |
| At least one test positive | 86.4 (65.1, 97.1) | 94.7 (92.0, 96.7) | 47.5 (31.5, 63.9) | 99.2 (97.7, 99.8) | 40 |
| Both tests positive | 31.8 (13.9, 54.9) | 99.8 (98.6, 100.0) | 87.5 (47.4, 99.7) | 96.3 (94.0, 97.9) | 8 |
418 specimen pairs (406 enrolled, 12 spikes) included in analysis, 22 specimens with event (5.3%).