Figure 6.

Mice administered GBP beginning 24 h after stroke recover forelimb function, even after treatment has been discontinued. (A) Experimental scheme of B and C. (B) Recovery of forelimb skilled function was assessed using the horizontal ladder rung walking test. Mean and SEM (mixed model with repeated measures using compound symmetry covariance structure and controlled on baseline values. For the 54 and 61 DPI comparison, time was used as categorical variable in the model *P < 0.05, **P < 0.01; vehicle n = 10 and GBP n = 10). (C) Recovery of forelimb symmetry was assessed using the cylinder test. Mean and SEM (mixed model with repeated measures using compound symmetry covariance structure. For the 54 and 61 DPI comparison, time was used as categorical variable in the model **P < 0.01, ***P < 0.001; vehicle n = 10 and GBP n = 10).