Table I.
Demographics, comorbidities, presenting factors for each age group separated by etiology.
| Acute on chronic patients | |||
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| |||
| Age ≤ 50 N = 39 | Age > 50 N = 80 | p-value | |
|
| |||
| Age a | 42.8 (6.2) | 57.3 (11.9) | <.01 |
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| |||
| Gender (female) | 18 (46.2) | 29 (36.3) | .30 |
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| |||
| Race (nonwhite) | 4 (10.3) | 6 (7.6) | .63 |
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| |||
| BMI | 28.5 (6.2) | 28.2 (13.8) | .56 |
|
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| Smoking history | |||
| Former | 33 (84.6) | 44 (55.0) | .01 |
| Current | 3 (7.7) | 16 (20.0) | |
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| |||
| Atrial fibrillation | 2 (5.1) | 17 (21.3) | .02 |
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| Diabetes | 14 (35.9) | 26 (32.5) | .71 |
|
| |||
| Chronic kidney disease | 8 (20.5) | 13 (16.3) | .57 |
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| |||
| Creatinine | 1.11 (0.74) | 1.31 (1.41) | .21 |
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| COPD | 8 (20.5) | 19 (23.8) | .69 |
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| Hypercoagulable diagnosis | 7 (18.0) | 5 (6.3) | .05 |
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| |||
| Cancer | 1 (2.6) | 12 (15.0) | .09 |
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| Prior ipsilateral intervention | 25 (64.1) | 60 (75.0) | .22 |
|
| |||
| Preoperative anticoagulation | 11 (28.2) | 24 (30.0) | .84 |
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| |||
| Preoperative antiplatelet | 18 (46.2) | 52 (65.0) | .05 |
|
| |||
| Rutherford Class | |||
| I | 4 (10.3) | 6 (7.5) | |
| IIa | 12 (30.8) | 33 (41.3) | .73 |
| IIb | 21 (53.9) | 37 (46.3) | |
| III | 2 (5.1) | 4 (5.0) | |
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| Thrombus burden on initial imaging b | |||
| Suprainguinal | 9 (23.1) | 24 (30.0) | .95 |
| Femoral-popliteal | 26 (66.7) | 78 (97.5) | .08 |
| Tibial | 17 (43.6) | 45 (56.3) | .94 |
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| |||
| > 6hrs to operating room | 24 (61.5) | 29 (36.3) | .01 |
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| De novo thrombosis patients | |||
|
| |||
| Age ≤ 50 N = 42 | Age > 50 N = 71 | p-value | |
|
| |||
| Age | 42.7 (7.0) | 69.5 (12.4) | <.01 |
|
| |||
| Gender (female) | 22 (52.4) | 34 (47.9) | .64 |
|
| |||
| Race (nonwhite) | 9 (21.4) | 11 (15.5) | .49 |
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| |||
| BMI | 29.8 (7.9) | 30.0 (7.5) | .55 |
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| |||
| Smoking history | |||
| Former | 28 (66.7) | 26 (36.6) | <.01 |
| Current | 1 (2.4) | 13 (18.3) | |
|
| |||
| Atrial fibrillation | 7 (16.7) | 23 (32.4) | .07 |
|
| |||
| Diabetes | 9 (21.4) | 24 (33.8) | .16 |
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| Chronic kidney disease | 1 (2.4) | 11 (15.5) | .03 |
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| |||
| Creatinine | 1.10 (0.69) | 1.38 (1.06) | .14 |
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| |||
| COPD | 2 (4.8) | 15 (21.1) | .02 |
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| |||
| Hypercoagulable diagnosis | 4 (9.5) | 7 (9.9) | .95 |
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| |||
| Cancer | 1 (2.4) | 7 (9.9) | .17 |
|
| |||
| Prior ipsilateral intervention | 4 (9.5) | 11 (15.5) | .37 |
|
| |||
| Preoperative anticoagulation | 5 (11.9) | 15 (21.1) | .22 |
|
| |||
| Preoperative antiplatelet | 6 (14.3) | 30 (42.3) | <.01 |
|
| |||
| Rutherford Class | |||
| I | 4 (9.5) | 6 (8.5) | |
| IIa | 16 (38.1) | 28 (39.4) | .26 |
| IIb | 17 (40.5) | 35 (49.3) | |
| III | 5 (11.9) | 2 (2.8) | |
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| |||
| Thrombus burden on initial imaging b | |||
| Suprainguinal | 10 (23.8) | 17 (23.9) | .75 |
| Femoral-popliteal | 33 (78.6) | 69 (97.2) | .14 |
| Tibial | 18 (42.9) | 43 (60.6) | .23 |
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| Source of embolism (N=57) c | |||
| Proximal arterial source | 26 (81.3) | 2 (7.8) | <.01 |
| Cardiac | 6 (18.8) | 24 (92.3) | |
|
| |||
| > 6hrs to operating | 9 (21.4) | 30 (42.3) | .02 |
a
Continuous variables are displayed as summary measure of mean (standard deviation) and P value from Student t-test when the variable is normally distributed. Categorical variables are summarized by N (%), and P values are calculated from the X2 test.
b
Thrombus identified on initial imaging – each level is not mutually exclusive
c
Source of embolism was identified on imaging of 57 de novo thrombosis/embolism patients
BMI, body mass index; COPD, chronic obstructive pulmonary disease.