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. 2023 Jan 31;22:22. doi: 10.1186/s12943-022-01712-8

Fig. 3.

Fig. 3

A glance at CAR T cell-based therapeutic prospect in brain cancer management. CAR T cells recognize some brain tumor-specific antigens that are targeted with an ambition to eliminate brain cancer cells. Some malignant growths in the brain can damage the BBB and help CAR T cells to cross the BBB to reach the tumor site. In addition, some delivery strategies allow delivering CAR T cells to the tumor site enabling the achievement of better therapeutic efficacy in brain tumor management