Table 1.
Clinical Characteristics of Participants
| Characteristics | HC (n = 10) | CSVD (n = 34) | P-value |
|---|---|---|---|
| Age (y), mean ± SD | 62.20 ± 7.22 | 63.88 ± 4.21 | 0.356 |
| Sex (female), n (%) | 2 (20) | 10 (29) | 0.702 |
| History, n (%) | |||
| Smoking | 6 (60) | 15 (44) | 0.481 |
| Ischemic heart disease | 2 (20) | 13 (38) | 0.452 |
| Diabetes mellitus | 2 (20) | 21 (62) | 0.031* |
| Hpertension | 8 (80) | 26 (77) | 1.000 |
| Dyslipidemia | 8 (80) | 26 (77) | 1.000 |
| Laboratory parameters | |||
| SBP (mmHg), mean ± SD | 136.20 ± 18.15 | 149.65 ± 17.61 | 0.041* |
| DBP (mmHg), median (P25, P75) | 81.00 (78.50, 88.25) | 82.00 (75.00, 88.00) | 0.757 |
| TC (mmol/L), median (P25, P75) | 3.69 (3.52, 5.93) | 3.77 (3.31, 4.17) | 0.262 |
| HDL (mmol/L), median (P25, P75) | 0.99 (0.83, 1.03) | 1.03 (0.89, 1.22) | 0.103 |
| LDL (mmol/L), median (P25, P75) | 2.09 (1.86, 3.75) | 2.20 (1.64, 2.47) | 0.217 |
| HBA1c (%), median (P25, P75) | 5.80 (5.58, 5.93) | 6.55 (5.63, 7.88) | 0.047* |
| Homocysteine (μmol/L), median (P25, P75) | 12.50 (11.05, 13.25) | 13.50 (9.35, 17.53) | 0.453 |
SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, HDL high-density protein, LDL low-density protein, HBA1c hemoglobin A1c
*P < 0.05 is significant