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CUB increases apoptosis of GBM cells. a The structure of CUB. b The effects of CUB on cell viability of U87, U251 GBM cell lines and normal human astrocytes cells. c, d Clone formation assay of U87 c and U251 d cells treated with CUB. e Apoptosis measurements of GBM cells with CUB (10, 20 μM) incubation for 12(Additional file: Fig. S1a), 24 h. Data represents the mean ± SEM (n = 3). Statistical analysis was performed using one-way ANOVA. *P < 0.05, **P < 0.01, and ***P < 0.001
