TABLE 1.

Hydrolytic enzymes and proteins with cell wall and extracellular targets

Enzyme	Gene	Location	Comments	Reference(s)
Cell wall substrates
Exo-β-(1,3)-glucanase	EXG (XOG1)	Cell wall, extracellular	Cell wall morphogenesis	75, 307, 308, 361, 387, 428, 429
β-1,3-glucan transferase	BGL2	Cell wall	Cell wall metabolism	122, 178, 196, 466, 471
Chitinase	CHT1-3	Periplasm, cell wall, extracellular	Hydrolytic enzyme, cell wall morphogenesis	141, 170, 346, 347
β-N-acetylglucosaminidase	HEX1	Periplasmic, extracellular	Hydrolytic enzyme, virulence factor?	55, 221, 365, 426, 519
Transglutaminase		Cell wall	Covalent cross-links?	456
Extracellular substrates
Secreted aspartyl proteinase	SAP1-9	Extracellular, cell surface	Putative virulence factor, gene expression condition dependent	1, 3, 18, 31, 84, 99–101, 109, 147, 157, 205, 206, 214, 215, 232, 233, 277, 348–350, 353, 359, 370, 372, 378, 379, 381, 397, 433–435, 441, 445–448, 450, 451, 509–511, 514, 515, 552, 570, 574
Phospholipase
Phospholipase A		Cell wall, surface, extracellular	Hydrolytic enzyme	23, 174, 425, 427
Phospholipase B	PLB1	Extracellular	Hydrolytic enzyme, putative virulence factor	19, 217, 473, 533
Phospholipase C		Extracellular	Hydrolytic enzyme	425, 427
Lysophospholipase		Cell wall, surface, extracellular	Hydrolytic enzyme	19, 23, 174, 355, 425, 427, 533
Lysophospholipase-transacylase		Extracellular	Hydrolytic enzyme, putative virulence factor	19, 217, 533, 534
Esterase		Extracellular	Hydrolytic enzyme	56, 419, 449, 551
Glucoamylase		Extracellular	Hydrolytic enzyme	82
Hemolytic factor		Cell wall, extracellular	Hydrolytic enzyme	317
Acid phosphatase		Periplasmic, surface	Hydrolytic enzyme	78, 105, 391, 547
Lipase	LIP1	Extracellular	Hydrolytic enzyme	148
Hyaluronidase		Extracellular	Hydrolytic enzyme, virulence factor?	499, 500
Chondroitan sulfatase		Extracellular	Hydrolytic enzyme, virulence factor?	499, 500
Metallopeptidase		Cell wall, extracellular?	Hydrolytic enzyme	120, 121
Trehalase		Cell wall, extracellular	Hydrolytic enzyme	362, 454