Table 3.
Symptom Comparison Between Viruses, Adjusted for Age
| Symptom/Presentation | Astrovirus vs Norovirus | Sapovirus vs Norovirus | Astrovirus vs Sapovirus |
|---|---|---|---|
| Estimate | Estimate | Estimate | |
| (95% CI) | (95% CI) | (95% CI) | |
| Diarrhea, PRa | 1.18 (1.08–1.29) | 1.02 (0.93–1.12) | 1.17 (1.05–1.30) |
| Vomiting, PRa | 1.00 (0.89–1.12) | 1.00 (0.95–1.05) | DNC |
| Fever, PRa | 1.38 (1.06–1.79) | 1.00 (0.78–1.28) | 1.57 (1.13–2.18) |
| ED presentation (day of illness), difference in mediansb | 1.2 (0.2–2.0) | 0.9 (−0.5 to 2.3) | 0.5 (−0.8 to 1.6) |
| Duration (hrs), Difference in Mediansb,c | |||
| Diarrhea | 24.8 (7.2–55.3) | 8.5 (−11.6 to 33.7) | 21.6 (−14.7 to 51.7) |
| Vomiting | 9.1 (2.8–36.5) | 24.8 (9.6–31.7) | −10.2 (−25.3 to 18.3) |
| Maximal Events, Difference in Mediansb,d | |||
| Diarrhea | 1.9 (0.8–3.0) | 0.0 (−0.8 to 1.0) | 2.0 (0.3–2.8) |
| Vomiting | −4.0 (−5.0 to −2.0) | −0.3 (−3.5 to 0.7) | −3.0 (−4.0 to 0.1) |
Abbreviations: CI, confidence interval; DNC, did not converge; ED, emergency department; PR, prevalence ratio.
aPrevalence ratio estimates are based on a log-binomial model adjusted for age that included all cases of the 2 viruses being compared. Cases with codetected pathogens were excluded.
bDifference estimates are based on a quantile regression model adjusted for age that included all cases of the 2 viruses being compared. Cases with codetected pathogens were excluded.
cDuration was measured from symptom presentation to resolution.
dMaximal events are measured within a 24-hour period.