Skip to main content
. 2021 Oct 26;113(12):1670–1682. doi: 10.1093/jnci/djab192

Table 2.

Net annualized patient out-of-pocket costs associated with cancer by phase of care, SEER-Medicare 2007-2013a,b,c

Cancer site Medical services (Medicare parts A and B)
Prescription drugs covered through pharmacy benefit (Medicare part D)
Medical services and prescription drugs
Initial Continuing End-of-life cancer death Initial Continuing End-of-life cancer death Initial Continuing End-of-life cancer death
Bladder $1472 $503 $3195 $154 $119 $201 $1626 $622 $3396
Brain $5751 $975 $5901 $522 $247 $479 $6273 $1222 $6380
Breast $2206 $384 $2852 $202 $167 $275 $2408 $551 $3127
Cervix uteri $3038 $349 $3148 −$6 −$36 $29 $3032 $313 $3177
Colorectal $2641 $482 $3857 $66 $30 $91 $2706 $512 $3948
Esophagus $4196 $664 $4459 $336 $113 $210 $4532 $777 $4669
Hodgkin lymphoma $3802 $617 $4201 $378 $75 $384 $4180 $693 $4585
Kidney $1693 $606 $3388 $309 $222 $938 $2003 $827 $4326
Leukemia $1973 $797 $5176 $642 $413 $582 $2615 $1210 $5758
 AML $6093 $1056 $7039 $1267 $335 $639 $7359 $1392 $7678
 CLL $1318 $790 $3393 $122 $117 $333 $1440 $907 $3726
 CML $1572 $799 $4342 $2456 $2341 $946 $4028 $3141 $5288
Liver $2746 $970 $2745 $577 $466 $773 $3323 $1436 $3517
Lung $3140 $780 $4003 $460 $309 $546 $3601 $1089 $4550
 NSCLC $3050 $776 $3930 $470 $312 $588 $3519 $1089 $4518
 SCLC $4461 $861 $4474 $325 $236 $274 $4786 $1097 $4748
Melanoma $662 $340 $2980 $123 $95 $440 $786 $434 $3420
Myeloma $3562 $1532 $4132 $2576 $1593 $1818 $6138 $3125 $5950
Non-Hodgkin lymphoma $3767 $848 $4940 $219 $88 $297 $3987 $936 $5237
Oral cavity or pharynx $3029 $465 $3978 $161 $36 $186 $3191 $500 $4164
Ovary $3166 $902 $3907 $154 $6 $142 $3320 $908 $4049
Pancreas $4280 $1083 $4158 $819 $519 $871 $5099 $1602 $5029
Prostate $1819 $335 $2830 $95 $48 $533 $1914 $382 $3363
Stomach $3116 $534 $4007 $308 $145 $164 $3424 $678 $4172
Thyroid $1354 $415 $3347 $228 $177 $434 $1582 $592 $3782
Uterus $1944 $337 $3187 $40 $15 $146 $1984 $352 $3333
All sites combined $2200 $466 $3823 $243 $127 $448 $2443 $593 $4271
a

Includes patients diagnosed with in-situ and invasive cancers. AML = acute myeloid leukemia; CLL = chronic lymphocytic leukemia; CML = chronic myeloid leukemia; NSCLC = non-small cell lung cancer; SCLC = small cell lung cancer; SEER = Surveillance, Epidemiology, and End Results Program.

b

Costs associated with cancer are estimated as the difference between cancer cases and matched controls. All estimates in 2019 US dollars.

c

Out-of-pocket costs estimated from patient responsibility for medical services (including infusion drugs) under Medicare Parts A/B claims. Out-of-pocket costs for oral prescription drugs estimated directly from Medicare Part D claims.