TABLE 1.

Characteristics of Children Younger Than 5 Yrs With Nosocomial and Community-acquired RSV-related In-hospital Death

	Nosocomial (n = 231)	Community-acquired (n = 931)	P
Male sex	107 (46.3)	500 (53.7)	0.05
Age at death (mo)	5.4 (2.5-12.1)	6.0 (2.6-13.0)	0.24
Neonatal death	18 (7.8)	38 (4.1)	0.03
<3 mo at death	66 (28.6)	244 (26.2)	0.51
<6 mo at death	120 (51.9)	452 (48.5)	0.38
Year of death	2012 (2006-2016)	2011 (2006-2015)	0.12
LMIC	32 (13.9)	236 (25.3)	<0.001
UMIC	76 (32.9)	338 (36.3)	0.36
HIC	123 (53.2)	357 (38.3)	<0.001
Comorbidity*	202 (87.4)	527 (56.6)	<0.001
Congenital heart disease	96 (41.6)	209 (22.4)	<0.001
Chronic lung disease	42 (18.2)	112 (12.0)	0.02
Genetic disease	48 (20.8)	134 (14.4)	0.02
Down syndrome	18 (7.8)	47 (5.0)	0.11
Neurological disease	39 (16.9)	135 (14.5)	0.36
Immune disorder	15 (6.5)	31 (3.3)	0.04
Other	68 (29.4)	139 (14.9)	<0.001
Prematurity*	106 (45.9)	225 (24.2)	<0.001
Gestational age (weeks)	36.0 (32.0–38.3); n = 174	38.0 (34.0–39.0); n = 496	0.004
Birth weight (kgs)	2.5 (1.7–3.1); n = 168	2.7 (2.0–3.2); n = 449	0.02
Breastfeeding until age ≤4 mo	36/139 (25.9)	161/404 (39.9)	0.003
Length of hospital stay (d)	23.0 (9.8–53.3); n = 230	9.0 (4.0–20.0); n = 901	<0.001
Intensive care unit (ICU) admission	209/216 (96.8)	641/868 (73.8)	<0.001
Length of ICU stay (d)	14.0 (7.0–30.0); n = 194	10.0 (4.0–21.0); n = 601	<0.001
Respiratory support	210/210 (100)	685/686 (99.9)	1.00
Mechanical ventilation	186/230 (80.9)	611/902 (67.7)	<0.001
Duration of respiratory support (d)	14.0 (7.0–29.0); n = 195	10.0 (4.0–20.0); n = 588	<0.001

Data are presented as n (%), n/N (%), or median (IQR).

^*Considered absent when missing.

HIC indicates high-income country; LMIC, low-income and lower-middle-income country; UMIC, upper-middle-income country.