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. 2023 Jan 31;2023(1):CD005562. doi: 10.1002/14651858.CD005562.pub3

Summary of findings 2. Group cognitive stimulation compared to no cognitive stimulation (post‐treatment) in people with dementia.

Group cognitive stimulation compared to no cognitive stimulation (post‐treatment) in people with dementia
Patient or population: people with dementia
Setting: care homes and long‐term care facilities; community settings including daycare and outpatients
Intervention: group cognitive stimulation
Comparison: no cognitive stimulation (post‐treatment)
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with no cognitive stimulation (post‐treatment) Risk with group cognitive stimulation
Cognition
Assessed with various brief cognitive tests including: ADAS‐Cog, MMSE, Global Cognitive Score; Mattis Dementia Rating Scale, MoCA, ENB2   SMD 0.43 SD higher
(0.26 higher to 0.59 higher) 1637
(27 RCTs) ⊕⊕⊕⊝
Moderate a Group cognitive stimulation probably results in a small increase in cognition.
Quality of Life: self‐report
Assessed with: QoL‐AD   SMD 0.28 SD higher
(0.05 higher to 0.52 higher) 1058
(13 RCTs) ⊕⊕⊝⊝
Low bc Group cognitive stimulation may result in a slight increase in self‐reported quality of life.
Communication and social interaction
Assessed with: Holden Communication Scale; NOSGER‐Social Behaviour subscale; Narrative language ‐ communicative abilities   SMD 0.53 SD higher
(0.36 higher to 0.7 higher) 702
(7 RCTs) ⊕⊕⊕⊕
High Group cognitive stimulation results in an increase in communication and social interaction.
Mood: self‐reported
assessed with: Geriatric Depression Scale (14 and 30‐item versions); CESD‐R   SMD 0.2 SD higher
(0.06 lower to 0.45 higher) 299
(6 RCTs) ⊕⊕⊕⊝
Moderate d Group cognitive stimulation probably results in a slight improvement in self‐reported mood.
Mood: interviewer/staff‐rated
Assessed with: Cornell Scale for Depression in Dementia; NOSGER‐Mood subscale; Montgomery‐Asberg Depression Rating Scale   SMD 0.4 SD higher
(0.14 higher to 0.67 higher) 959
(10 RCTs) ⊕⊕⊕⊝
Moderate b Group cognitive stimulation probably results in a small improvement in interviewer/staff‐rated mood.
Instrumental ADL
Assessed with: Lawton‐Brody IADL scale; Disability Assessment for Dementia; NOSGER IADL subscale; ADCS‐ADL scale; Rapid Disability Rating Scale   SMD 0.2 SD higher
(0.05 higher to 0.35 higher) 687
(8 RCTs) ⊕⊕⊕⊕
High Group cognitive stimulation results in a slight increase in Instrumental ADL.
Behaviour that challenges
assessed with: NPI; NPI‐Agitation subscale; NOSGER‐Challenging Behaviour subscale; BEHAVE‐AD; Dementia Behaviour Disturbance subscale   SMD 0.33 SD higher
(0.11 higher to 0.54 higher) 754
(8 RCTs) ⊕⊕⊕⊝
Moderate a Group cognitive stimulation probably results in a slight improvement in behaviour that challenges.
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

ADL: activities of daily living; CI: confidence interval; OR: odds ratio; RR: risk ratio
GRADE Working Group grades of evidenceHigh certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

a Downgraded one point for inconsistency as moderate heterogeneity was present.

b Downgraded one point for inconsistency as substantial heterogeneity was present.

c Downgraded one point for imprecision as 95% CIs included both a clinically important and a negligible effect.

d Downgraded one point for imprecision as fewer than 400 participants.