Justo‐Henriques 2022.
Study characteristics | ||
Methods | RCT | |
Participants | N = 59 (36F/23M) Formal diagnosis of a neurocognitive disorder according to DSM‐5 criteria (51% Alzheimer's disease) No details available regarding AChEI medication Mean MMSE: 23.2 (SD 3.2) Age 78.9 (SD; 7.5; range 65‐98) Community |
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Interventions | Home‐based Individual cognitive stimulation delivered by clinical psychologist (N = 30) Treatment‐as‐usual (N = 29) |
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Outcomes | Cognition: MoCA, MMSE Quality of life: QoL‐AD (self‐report) Mood: GDS‐15 ADL: adapted Lawton‐Brody Index |
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Notes | 45 minutes, once a week, for 47 weeks | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "Non‐stratified permuted block randomization process" carried out by blinded investigator using computer software |
Allocation concealment (selection bias) | Low risk | "Allocation was unknown to participants and the therapist until the intervention started". |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Evaluator blinded to participant allocation |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Relatively high level of attrition (8/30 in intervention group), but lengthy treatment period (47 weeks) and reasons given. Similar attrition in control group |
Selective reporting (reporting bias) | Low risk | Results for all outcomes cited in Methods section were reported. |
Other bias ‐ training and supervision | Low risk | Experienced therapist received additional training. |
Other bias ‐ treatment manual | Low risk | The study protocol provided a detailed account of the activities for each session. |