Kim 2016.
Study characteristics | ||
Methods | RCT | |
Participants | N = 53 (37F/16M) Probable Alzheimer's Disease (NINCDS and ADRDA criteria) All participants receiving 'pharmacotherapy' for dementia Mean MMSE 18.0 (SD 5.8) Age 78.5 (SD 1.5; range 61‐94) Community residents attending dementia centre |
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Interventions | Multi‐domain cognitive stimulation (N = 32) Control group (N = 21) |
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Outcomes | Cognition: CERAD (Korean version), including word fluency; short Boston naming test; tests of praxis, recall and recognition; MMSE Mood: Geriatric Depression Scale Quality of Life: QoL‐AD (Korean version) (self‐rated and proxy) Clinical Dementia Rating Scale |
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Notes | 1 hour, 5 times a week for 6 months | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Description of randomisation unclear ('using random numbering') |
Allocation concealment (selection bias) | Unclear risk | No mention of randomisation being carried out independently |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No information about blinding |
Incomplete outcome data (attrition bias) All outcomes | High risk | No attrition from intervention group; 34% attrition from control group |
Selective reporting (reporting bias) | Low risk | All outcome measures mentioned in methods were reported. |
Other bias ‐ training and supervision | Low risk | "Implementation and management of the cognitive intervention program were carried out by two skilled and professionally educated occupational therapists." |
Other bias ‐ treatment manual | Low risk | Clear structure for the intervention |