Marinho 2021.
Study characteristics | ||
Methods | RCT | |
Participants | N = 47 (29F/18M) Clinical diagnosis of dementia according to DSM‐IV criteria (MMSE 10‐24) All participants receiving AChEI medication Clinical Dementia Rating: 23 mild; 24 moderate Age 77.8 (SD; 8.4; range 60‐91) Outpatients |
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Interventions | Cognitive stimulation groups (N = 23) Treatment‐as‐usual (N = 24) |
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Outcomes | Cognition: ADAS‐Cog Quality of life: QoL‐AD (self‐report and proxy) Mood: Cornell Scale for Depression in Dementia ADL: ADCS‐ADL scale Caregiver outcomes: Zarit Burden Interview |
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Notes | 45 minutes, 2 times a week, for 7 weeks (both weekly sessions on same day, separated by short break) | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Used a random list generated by a computer program; stratified by dementia severity |
Allocation concealment (selection bias) | Unclear risk | Not detailed who carried out the randomisation, and whether external to the study |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Outcome assessments carried out by researchers blind to the intervention |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Data provided for intention‐to‐treat analysis; reasons for dropouts described |
Selective reporting (reporting bias) | Low risk | Results for all outcomes reported |
Other bias ‐ training and supervision | Low risk | Facilitators trained by International CST centre |
Other bias ‐ treatment manual | Low risk | Used Brazilian CST manual, adapted from Spector 2006 |