Table 3.
Standard of care and kidney disease improving global outcomes bundle intervention.
| Control | Intervention KDIGO Bundle |
|---|---|
| Standard care | Discontinuation of all nephrotoxic agents if possible |
| ACEi and ARBs continued according to ACC recommendations | Discontinuation of ACE inhibitors and ARBs for the first 2 days after surgery |
| MAP will be kept >65 mmHg | Close monitoring of serum creatinine and urinary output |
| CVP between 8 and 10 mmHg | Avoidance of hyperglycemia by close monitoring |
| _ | Consideration of alternatives to radio contrast agents |
| _ | Hemodynamic monitoring and optimization according to a hemodynamic algorithm |
ACC, American College of Cardiology; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin-receptor blocker; CVP, central venous pressure; KDIGO, Kidney Disease: Improving Global Outcomes; MAP, mean arterial pressure.