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Schematic models of MSCRAMMs from S. aureus. The MSCRAMMs shown are the ones with affinity for fibronectin (FnbpA and FnbpB), collagen (CNA), and fibrinogen (CLF, clumping factor). S, signal sequence; U or A, unique nonrepetitive sequence; δ, upstream repeat sequences; D, B, or R: repeated domains; W, cell wall-spanning domain; M, hydrophobic membrane-spanning domain; C, positively charged carboxy terminus. Reprinted from reference 139 with permission of the authors and the publisher.
