Table 3.
Outcomes | Dose of hepatitis B vaccine | Mother’s HBsAg status |
Survey time |
||||||
---|---|---|---|---|---|---|---|---|---|
Negative (N = 1117) |
Positive (N = 146) |
2014 (N = 1013) |
2020 (N = 1007) |
||||||
Adjusted odds ratio (95% CI)* | P value | Adjusted odds ratio (95% CI)* | P value | Adjusted odds ratio (95% CI)* | P value | Adjusted odds ratio (95% CI)* | P value | ||
HBV infection | 5 μg# | Reference | Reference | Reference | Reference | ||||
10 μg# | 0.57 (0.13–2.58) | .47 | 0.27 (0.03–2.78) | .27 | 0.53 (0.06–5.11) | .58 | 0.27 (0.07–1.12) | .071 | |
5 μg& | Reference | Reference | Reference | Reference | |||||
10 μg& | 0.49 (0.11–2.20) | .35 | 0.24 (0.02–2.55) | .24 | 0.49 (0.05–4.95) | .55 | 0.23 (0.06–0.92) | .038 | |
HBsAg carriage | 5 μg# | Reference | Reference | Reference | Reference | ||||
10 μg# | – | – | 0.44 (0.04–5.4) | .52 | 1.80 (0.17–19.46) | .63 | 0.26 (0.02–4.13) | .26 | |
5 μg& | Reference | Reference | Reference | Reference | |||||
10 μg& | – | – | 0.40 (0.03–4.87) | .47 | 1.63 (0.14–18.69) | .69 | 0.24 (0.02–3.90) | .24 | |
Anti-HBc positive | 5 μg# | Reference | Reference | Reference | Reference | ||||
10 μg# | 0.54 (0.12–2.45) | .43 | 0.27 (0.03–2.82) | .27 | 0.49 (0.05–5.19) | .56 | 0.23 (0.06–0.96) | .043 | |
5 μg& | Reference | Reference | Reference | Reference | |||||
10 μg& | 0.46 (0.10–2.07) | .31 | 0.24 (0.02–2.60) | .24 | 0.51 (0.05–5.52) | .58 | 0.20 (0.05–0.81) | .025 |
*Adjusted for resident (urban or rural), birth year (<2002 or ≥2002), gender (male or female), and birth place (hospital, home, or unknown) in the stratification analysis by the mother’s status of HBsAg (negative or positive). For the survey time stratification, the mother’s HBsAg status (positive, negative, or unknown), resident, gender, and birth place were included in the model.
#Referred to the treated dose of hepatitis B vaccine; &Referred to the surveyed dose of hepatitis B vaccine.