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. 2023 Feb 1;9(5):eadd3607. doi: 10.1126/sciadv.add3607

Table 3. Volume of subcortical ROIs (ipsilateral and contralateral) is stroke.

This table shows the mean volume of several representative ROIs in the contralateral and ipsilateral side of the stroke, the effect size between the two distributions (i.e., the asymmetry), and the correlation between the stroke lesion size and the volumes of the ROIs, including P values computed with Student’s t test. We only included in this analysis stroke lesions that had more than two-thirds of their volume in one of the two hemispheres (N = 598).

Region Hippocampus Amygdala Thalamus Putamen Caudate
Contralateral volume, mean and SD (mm3) 4861 ± 560 2113 ± 274 7131 ± 803 5442 ± 686 4551 ± 483
Ipsilateral volume, mean and SD (mm3) 4831 ± 560 1999 ± 310 5958 ± 1420 4642 ± 1147 4096 ± 655
Effect size: Contralateral versus ipsilateral 0.05 0.39 1.02 0.85 0.79
Correlation of lesion and contralateral volumes and P value 0.011 (P = 0.78) −0.027 (P = 0.50) 0.021 (P = 0.61) 0.052 (P = 0.20) 0.07 (P = 0.07)
Correlation of lesion and ipsilateral volumes and P value 0.003 (P = 0.93) −0.300 (P < 10−13) −0.410 (P < 10−24) −0.494 (P < 10−37) −0.349 (P < 10−17)