Table 3. Conditions for differentiating iTfh0, iTfh1, iTfh2, and iTfh17 Cells.

Cell type	Cytokines	Neutralizing antibodies
iTh0	No cytokines	No antibodies
iTh1	20 ng/ml IL-12	Anti-IL-4, anti-TGF-β
iTh2	50 ng/ml IL-4	Anti-IFN-γ, anti-TGF-β
iTh17	50 ng/ml IL-6, 2 ng/ml TGF-β	Anti-IFN-γ, anti-IL-4
iTfh1	100 ng/ml IL-6, 50 ng/ml IL-21, 1 ng/ml IL-12	Anti-IL-4, anti-TGF-β
iTfh2	100 ng/ml IL-6, 50 ng/ml IL-21, 20 ng/ml IL-4	Anti-IFN-γ, anti-TGF-β
iTfh17	100 ng/ml IL-6, 50 ng/ml IL-21, 0.1 ng/ml TGF-β	Anti-IFN-γ, anti-IL-4