Table 2.
Adipocyte size frequency distribution in VAT.
| Young adults | Aged adults | |||||
|---|---|---|---|---|---|---|
| mock | Day 7 | Day 22 | Mock | Day 7 | Day 22 | |
| Cells counted | 1531 | 2661 | 2088 | 1412 | 2872 | 2072 |
| Minimum | 68.7 | 48.2 | 45.6 | 72.6 | 80.1 | 78.7 |
| 25% percentile | 922.9 | 504 | 651.7 | 890.7 | 407.4 | 457.4 |
| Median | 2151 | 1171 | 1632 | 2307 | 893.3 | 1226 |
| 75% percentile | 3769.5 | 2066.4 | 2660.2 | 3894 | 1538.9 | 2276.4 |
| Maximum | 10854.1 | 6851.4 | 8137.5 | 14228.5 | 11990.5 | 19922.5 |
| Mean | 2459 | 1388**** | 1789**** | 2628# | 1142**** | 1551**** |
| Std. deviation | 1775 | 1068 | 1294 | 2067 | 1068 | 1408 |
| Std. error of mean | 45.35 | 20.7 | 28.3 | 55 | 19.9 | 30.9 |
| Lower 95% CI of mean | 2369.6 | 1346.9 | 1733.6 | 2520.6 | 1102.4 | 1490 |
| Upper 95% CI of mean | 2547.6 | 1428 | 1844.6 | 2736.4 | 1180.6 | 1611.3 |
The mean adipocyte sizes in the (epidydimal) VAT of young adult and aged hamsters at days 0 (mock), 7, and 22 after SARS-CoV-2 infection were compared in a two-sided Mann–Whitney test. For intergroup differences, the threshold for statistical significance was set to p < 0.05 Values with superscript symbols indicate significant differences (comparison of young adults with aged adults (the effect of age): #p < 0.05), and comparison of mock-treated and SARS-CoV-2-infected groups (the effect of infection) ****p < 0.0001).